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Deep brain structures

Also called Deep brain structures, Subcortical structures

The hidden machinery under the wrinkly surface that runs habits, senses and survival.

The deep parts of the brain lit up in a 3D model of the human brainOpen in 3D

The wrinkly outer layer of the brain, the cortex, gets most of the attention. But tucked underneath it is a whole hidden world of deep structures. These include the basal ganglia (which help pick your actions), the thalamus and hypothalamus (the sensory switchboard and the body's control center), the limbic system (memory and emotion), fluid-filled spaces called ventricles, and thick cables of white matter. Much of what keeps you alive, alert and feeling things happens down here, mostly without you noticing.

Where it is

Deep in the center of the brain, wrapped on all sides by the cortex and sitting on top of the brainstem.

What it does

Choosing actions

The basal ganglia help pick which movement or habit to run next, and hold back all the others.

Relaying the senses

The thalamus passes sight, sound, touch and taste up to the cortex, so you become aware of them.

Keeping the body in balance

The hypothalamus manages temperature, hunger, thirst, sleep and hormones, mostly on autopilot.

Memory and emotion

The limbic system, including the hippocampus and amygdala, helps form new memories and colors them with feeling.

Wiring and plumbing

White matter cables carry messages between regions, while fluid in the ventricles cushions and cleans the brain.

Think of it as the engine room below the deck of a ship: passengers only see the deck, but the engines, wiring and control rooms below keep everything running.

Inside the deep parts of the brain

  • Basal gangliaYour action selector: says "go" to one move and "no-go" to all the rest.
  • DiencephalonThe "in-between brain": home of the thalamus, hypothalamus and a few tiny glands.
  • Limbic systemThe brain's emotion and memory team, wrapped around its deep core.
  • Ventricular systemA hidden network of fluid-filled chambers that cushions and cleans the brain.
  • White matter pathwaysThe brain's wiring: bundles of fat-wrapped cables that let distant regions talk fast.

Works with

  • Basal gangliaThe action selectors that decide "go" or "no-go" for every move you make.
  • DiencephalonThe central core with the thalamus, hypothalamus and a few tiny glands.
  • Limbic systemThe memory and emotion circuit that wraps around the deep core.
  • Ventricular systemFluid-filled spaces that cushion the deep structures and carry away waste.
  • White matter pathwaysThe cable network that links the deep parts to the cortex and to each other.
  • BrainstemThe stalk below that connects all these deep parts to the spinal cord and body.

When it goes wrong

Movement disorders

Parkinson's disease and Huntington's disease both damage the basal ganglia circuits down here, which is why they affect movement so strongly.

Small deep strokes

Deep parts are fed by very thin arteries. If one gets blocked, it can cause a small "lacunar" stroke that may weaken or numb one side of the body.

Deep brain stimulation

Surgeons can place thin wires into deep targets to calm the symptoms of Parkinson's disease, tremor and dystonia, a kind of brain pacemaker.

For learning only, not medical advice. If you have a health concern, talk to a doctor.

Surprising facts

  • Nearly every sense you have, except smell, passes through the thalamus in the middle of your brain before you become aware of it.
  • Your body makes roughly half a liter of brain fluid every day, so the fluid bathing your brain is replaced several times a day.
  • More than 100,000 people with Parkinson's disease around the world have had thin wires placed deep in their brains to ease their symptoms.

Where the name comes from

"Subcortical", the scientific word for these parts, simply means "below the cortex". Cortex is Latin for "bark", like the bark wrapped around a tree.

Quick quiz

2 questions. Your answers are saved and come back in your daily review.

  1. Which of these is a job of the deep parts of the brain?

    Show the answer

    Choosing actions. The basal ganglia help pick which movement or habit to run next, and hold back all the others.

  2. Which part fits this description? "Like the engine room below the deck of a ship: passengers only see the deck, but the engines, wiring and control rooms below keep everything running."

    Show the answer

    Inside the brain. It is the deep parts of the brain. The hidden machinery under the wrinkly surface that runs habits, senses and survival.

Sources

  1. 13.2 The Central Nervous System, OpenStax, Anatomy and Physiology 2e
  2. Physiology, Cerebral Spinal Fluid, StatPearls, NCBI Bookshelf
  3. Deep brain stimulation for Parkinson's disease, Lasker Foundation

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