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Medulla oblongata

Also called Medulla oblongata, Myelencephalon

Your life-support center: breathing, heartbeat, blood pressure and swallowing on autopilot.

The medulla oblongata lit up in a 3D model of the human brainOpen in 3D

The medulla oblongata is the lowest part of the brainstem, where the brain joins the spinal cord. It runs the body's most vital automatic jobs: breathing, heart rate, blood pressure and swallowing. It also handles reflexes like coughing, gagging and vomiting. And it is where the main movement pathway crosses over, which is why the left side of the brain controls the right side of the body.

Where it is

At the very bottom of the brainstem, just above where the skull meets the neck. It becomes the spinal cord at the large hole in the base of the skull.

What it does

Breathing

A tiny group of cells here acts as the pacemaker for every breath you take.

Heart and blood pressure

It speeds up or slows down your heart and adjusts your blood vessels to keep blood pressure steady.

Protective reflexes

It runs swallowing, coughing, gagging and vomiting.

The great crossover

Most movement fibers from the cortex cross to the other side here, at a spot called the pyramidal decussation. That is why the left brain moves the right body.

Teaching the cerebellum

Two bumps on its front, called the olives, send error signals up to the cerebellum to help it learn.

Think of it as a hospital's life-support machine that never switches off, keeping you breathing and your heart beating even while you sleep.

Works with

  • Corticospinal tractThis main movement pathway runs through the medulla's front ridges, the pyramids, and crosses sides here.
  • Spinal cordThe medulla flows straight into the spinal cord.
  • Vagus nerve (X)This long nerve starts here and carries its orders to the heart, lungs and gut.
  • Glossopharyngeal nerve (IX)This nerve brings blood pressure and throat signals into the medulla.
  • Hypoglossal nerve (XII)This nerve leaves the medulla to move your tongue.
  • Climbing fibersIts olives send these fibers up to the cerebellum to help it learn from mistakes.

When it goes wrong

A danger zone

Serious damage here can stop breathing or the heartbeat, which is why injuries at the base of the skull are so dangerous.

Opioid overdose

Opioids quiet the breathing centers in the brainstem, including the medulla. In an overdose, breathing can slow and stop, which is why rescue medicines like naloxone save lives.

Lateral medullary stroke

A stroke on one side of the medulla can cause dizziness, a hoarse voice, trouble swallowing, and numbness of the face on one side and the body on the other. It is also called Wallenberg syndrome.

For learning only, not medical advice. If you have a health concern, talk to a doctor.

Surprising facts

  • The urge to breathe when you hold your breath comes mostly from carbon dioxide building up, not from running out of oxygen. Sensors in the medulla are among the main detectors.
  • Its vomiting trigger zone sits at one of the few spots where the brain's protective blood barrier is leaky, so it can "taste" the blood for poisons.

By the numbers

About 3 cmLength
75 to 90%Movement fibers that cross here

Where the name comes from

Latin for "elongated marrow". "Medulla" means marrow or core, and "oblongata" means lengthened, because it looks like a stretched-out top of the spinal cord.

Learn it in a lesson

Quick quiz

3 questions. Your answers are saved and come back in your daily review.

  1. Which of these is a job of the medulla oblongata?

    Show the answer

    Breathing. A tiny group of cells here acts as the pacemaker for every breath you take.

  2. The medulla oblongata is part of which larger structure?

    Show the answer

    Brainstem. It belongs to the brainstem.

  3. Which part fits this description? "Like a hospital's life-support machine that never switches off, keeping you breathing and your heart beating even while you sleep."

    Show the answer

    Medulla oblongata. It is the medulla oblongata. Your life-support center: breathing, heartbeat, blood pressure and swallowing on autopilot.

Sources

  1. Neuroanatomy, Medulla Oblongata, StatPearls, NCBI Bookshelf
  2. Medulla oblongata, Radiopaedia
  3. Neuroanatomy, Corticospinal Cord Tract, StatPearls, NCBI Bookshelf

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